Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function.
Thymic T cell development is dependent on a specialized epithelial microenvironment mainly composed of cortical and medullary thymic epithelial cells (TECs). The molecular programs governing the differentiation and maintenance of TECs remain largely unknown. Wnt signaling is central to the developme...
Үндсэн зохиолчид: | Zuklys, S, Gill, J, Keller, M, Hauri-Hohl, M, Zhanybekova, S, Balciunaite, G, Na, K, Jeker, LT, Hafen, K, Tsukamoto, N, Amagai, T, Taketo, M, Krenger, W, Holländer, G |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2009
|
Ижил төстэй зүйлс
Ижил төстэй зүйлс
-
Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells.
-н: Jeker, LT, зэрэг
Хэвлэсэн: (2008) -
Loss of thymus epithelial cell identity following the constitutive activation of the canonical Wnt pathway
-н: Zuklys, S, зэрэг
Хэвлэсэн: (2007) -
TGF- 2signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution
-н: Hauri-Hohl, M, зэрэг
Хэвлэсэн: (2008) -
TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.
-н: Hauri-Hohl, M, зэрэг
Хэвлэсэн: (2008) -
Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation.
-н: Hauri-Hohl, M, зэрэг
Хэвлэсэн: (2007)