Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.
Dilated cardiomyopathy (DCM), characterized by cardiac dilatation and contractile dysfunction, is a major cause of heart failure. Inherited DCM can result from mutations in the genes encoding cardiac troponin T, troponin C, and alpha-tropomyosin; different mutations in the same genes cause hypertrop...
Главные авторы: | , , , , , , , , |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2005
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