Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study
<p><strong>Background:</strong> Little is known about the effects of maintaining healthy sleep patterns on frailty transitions.</p> <p><strong>Methods:</strong> Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the assoc...
| Main Authors: | , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal article |
| Language: | English |
| Published: |
BioMed Central
2022
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| _version_ | 1797109636999938048 |
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| author | Zhu, Y Fan, J Lv, J Guo, Y Pei, P Yang, L Chen, Y Du, H Li, F Yang, X Avery, D Chen, J Chen, Z Yu, C Li, L |
| author2 | China Kadoorie Biobank Collaborative Group |
| author_facet | China Kadoorie Biobank Collaborative Group Zhu, Y Fan, J Lv, J Guo, Y Pei, P Yang, L Chen, Y Du, H Li, F Yang, X Avery, D Chen, J Chen, Z Yu, C Li, L |
| author_sort | Zhu, Y |
| collection | OXFORD |
| description | <p><strong>Background:</strong> Little is known about the effects of maintaining healthy sleep patterns on frailty transitions.</p>
<p><strong>Methods:</strong> Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions.</p>
<p><strong>Results:</strong> During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89–0.96), 0.76 (0.74–0.77), and 0.85 (0.82–0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00–1.18) and 1.42 (1.31–1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (<i>P</i> for trend < 0.001).</p>
<p><strong>Conclusions:</strong> Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults.</p> |
| first_indexed | 2024-03-07T07:44:19Z |
| format | Journal article |
| id | oxford-uuid:ae3bb410-5f9c-43a0-862c-79546bf95625 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:44:19Z |
| publishDate | 2022 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:ae3bb410-5f9c-43a0-862c-79546bf956252023-05-22T09:17:26ZMaintaining healthy sleep patterns and frailty transitions: a prospective Chinese studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ae3bb410-5f9c-43a0-862c-79546bf95625EnglishSymplectic ElementsBioMed Central2022Zhu, YFan, JLv, JGuo, YPei, PYang, LChen, YDu, HLi, FYang, XAvery, DChen, JChen, ZYu, CLi, LChina Kadoorie Biobank Collaborative Group<p><strong>Background:</strong> Little is known about the effects of maintaining healthy sleep patterns on frailty transitions.</p> <p><strong>Methods:</strong> Based on 23,847 Chinese adults aged 30–79 in a prospective cohort study, we examined the associations between sleep patterns and frailty transitions. Healthy sleep patterns included sleep duration at 7 or 8 h/d, without insomnia disorder, and no snoring. Participants who persisted with a healthy sleep pattern in both surveys were defined as maintaining a healthy sleep pattern and scored one point. We used 27 phenotypes to construct a frailty index and defined three statuses: robust, prefrail, and frail. Frailty transitions were defined as the change of frailty status between the 2 surveys: improved, worsened, and remained. Log-binomial regression was used to calculate the prevalence ratio (PR) to assess the effect of sleep patterns on frailty transitions.</p> <p><strong>Results:</strong> During a median follow-up of 8.0 years among 23,847 adults, 45.5% of robust participants, and 10.8% of prefrail participants worsened their frailty status, while 18.6% of prefrail participants improved. Among robust participants at baseline, individuals who maintained sleep duration of 7 or 8 h/ds, without insomnia disorder, and no-snoring were less likely to worsen their frailty status; the corresponding PRs (95% CIs) were 0.92 (0.89–0.96), 0.76 (0.74–0.77), and 0.85 (0.82–0.88), respectively. Similar results were observed among prefrail participants maintaining healthy sleep patterns. Maintaining healthy sleep duration and without snoring, also raised the probability of improving the frailty status; the corresponding PRs were 1.09 (1.00–1.18) and 1.42 (1.31–1.54), respectively. Besides, a dose-response relationship was observed between constantly healthy sleep scores and the risk of frailty transitions (<i>P</i> for trend < 0.001).</p> <p><strong>Conclusions:</strong> Maintaining a comprehensive healthy sleep pattern was positively associated with a lower risk of worsening frailty status and a higher probability of improving frailty status among Chinese adults.</p> |
| spellingShingle | Zhu, Y Fan, J Lv, J Guo, Y Pei, P Yang, L Chen, Y Du, H Li, F Yang, X Avery, D Chen, J Chen, Z Yu, C Li, L Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_full | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_fullStr | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_full_unstemmed | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_short | Maintaining healthy sleep patterns and frailty transitions: a prospective Chinese study |
| title_sort | maintaining healthy sleep patterns and frailty transitions a prospective chinese study |
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