Characterising the binding specificities of the subunits associated with the KMT2/Set1 histone lysine methyltransferase.
KMT2/Set1 is the catalytic subunit of the complex of proteins associated with Set1 (COMPASS) that is responsible for the methylation of lysine 4 of histone H3 (H3K4) in Saccharomyces cerevisiae. Whereas monomethylated H3K4 (H3K4me1) is found throughout the genome, di- (H3K4me2) and tri- (H3K4me3) me...
Main Authors: | Murton, B, Chin, W, Ponting, C, Itzhaki, L |
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Format: | Journal article |
Language: | English |
Published: |
2010
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