Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stemness level of a cell and determines its proliferative capacity, apoptosis propensity and response to treatment. Our stud...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
Elsevier
2022
|