Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations

The aim of this study was to discover if the forced inspired inert gas sinewave technique could be used to measure pulmonary blood flow, using nitrous oxide as the indicator gas, following inotropic stimulation of the heart by dobutamine, in the presence of a constant alveolar ventilation. Cardiac o...

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Main Authors: Williams, E, Sainsbury, M, Sutton, L, Xiong, L, Black, A, Whiteley, J, Gavaghan, D, Hahn, C
Format: Journal article
Published: 1998
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author Williams, E
Sainsbury, M
Sutton, L
Xiong, L
Black, A
Whiteley, J
Gavaghan, D
Hahn, C
author_facet Williams, E
Sainsbury, M
Sutton, L
Xiong, L
Black, A
Whiteley, J
Gavaghan, D
Hahn, C
author_sort Williams, E
collection OXFORD
description The aim of this study was to discover if the forced inspired inert gas sinewave technique could be used to measure pulmonary blood flow, using nitrous oxide as the indicator gas, following inotropic stimulation of the heart by dobutamine, in the presence of a constant alveolar ventilation. Cardiac output (range 1-4.5 L min(-1)) was measured in six dogs by thermodilution and by calculation from the sinusoidal expired partial pressures of argon and nitrous oxide using: (i) analytical equations and a conventional continuous ventilation three-compartment lung model, which did not include recirculation; and
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spelling oxford-uuid:aec7ac2c-c8ab-4bb3-b5f6-3a1e2752fadf2022-03-27T03:44:55ZPulmonary blood flow measured by inspiratory inert gas concentration forcing oscillationsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aec7ac2c-c8ab-4bb3-b5f6-3a1e2752fadfDepartment of Computer Science1998Williams, ESainsbury, MSutton, LXiong, LBlack, AWhiteley, JGavaghan, DHahn, CThe aim of this study was to discover if the forced inspired inert gas sinewave technique could be used to measure pulmonary blood flow, using nitrous oxide as the indicator gas, following inotropic stimulation of the heart by dobutamine, in the presence of a constant alveolar ventilation. Cardiac output (range 1-4.5 L min(-1)) was measured in six dogs by thermodilution and by calculation from the sinusoidal expired partial pressures of argon and nitrous oxide using: (i) analytical equations and a conventional continuous ventilation three-compartment lung model, which did not include recirculation; and
spellingShingle Williams, E
Sainsbury, M
Sutton, L
Xiong, L
Black, A
Whiteley, J
Gavaghan, D
Hahn, C
Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title_full Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title_fullStr Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title_full_unstemmed Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title_short Pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
title_sort pulmonary blood flow measured by inspiratory inert gas concentration forcing oscillations
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