Structural basis for mitotic centrosome assembly in flies
In flies, Centrosomin (Cnn) forms a phosphorylation-dependent scaffold that recruits proteins to the mitotic centrosome, but how Cnn assembles into a scaffold is unclear. We show that scaffold assembly requires conserved Leucine Zipper (LZ) and Cnn-Motif 2 (CM2) domains that co-assemble into a 2:2 c...
| Auteurs principaux: | , , , , , , , , |
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| Format: | Journal article |
| Publié: |
Cell Press
2017
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