Endothelin-1 increases susceptibility of isolated rat hearts to ischemia/reperfusion injury by reducing coronary flow.
Endothelin-1 (ET-1) is the most potent vasoconstrictor known to date, and it was proposed that this peptide plays a major role in myocardial ischemia/reperfusion injury. ET-1 could increase myocardial susceptibility to ischemia by two mechanisms: via coronary flow reduction and/or via direct, metabo...
Κύριοι συγγραφείς: | Groot, d, Illing, B, Horn, M, Urban, B, Haase, A, Schnackerz, K, Neubauer, S |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1998
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Effects of endothelin-1 in the isolated heart in ischemia/reperfusion and hypoxia/reoxygenation injury.
ανά: Neubauer, S, κ.ά.
Έκδοση: (1991) -
Protective effect of the specific endothelin-1 antagonist BQ610 on mechanical function and energy metabolism during ischemia/reperfusion injury in isolated perfused rat hearts.
ανά: Illing, B, κ.ά.
Έκδοση: (1996) -
Endothelin-1 contributes to ischemia/reperfusion injury in isolated rat heart-attenuation of ischemic injury by the endothelin-1 antagonists BQ123 and BQ610.
ανά: Han, H, κ.ά.
Έκδοση: (1995) -
Creatine kinase-deficient hearts exhibit increased susceptibility to ischemia-reperfusion injury and impaired calcium homeostasis.
ανά: Spindler, M, κ.ά.
Έκδοση: (2004) -
Mechanisms of the effects of nicorandil in the isolated rat heart during ischemia and reperfusion: a 31P-nuclear magnetic resonance study.
ανά: Horn, M, κ.ά.
Έκδοση: (2001)