Endothelin-1 increases susceptibility of isolated rat hearts to ischemia/reperfusion injury by reducing coronary flow.
Endothelin-1 (ET-1) is the most potent vasoconstrictor known to date, and it was proposed that this peptide plays a major role in myocardial ischemia/reperfusion injury. ET-1 could increase myocardial susceptibility to ischemia by two mechanisms: via coronary flow reduction and/or via direct, metabo...
Váldodahkkit: | Groot, d, Illing, B, Horn, M, Urban, B, Haase, A, Schnackerz, K, Neubauer, S |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
1998
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Geahča maid
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Effects of endothelin-1 in the isolated heart in ischemia/reperfusion and hypoxia/reoxygenation injury.
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