No association between interferon-gamma receptor-1 gene polymorphism and pulmonary tuberculosis in a Gambian population sample.

BACKGROUND: Tuberculosis (TB) is a major global cause of mortality and morbidity, and host genetic factors influence disease susceptibility. Interferon-gamma mediates immunity to mycobacteria and rare mutations in the interferon-gamma receptor-1 gene (IFNGR1) result in increased susceptibility to my...

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Main Authors: Awomoyi, A, Nejentsev, S, Richardson, A, Hull, J, Koch, O, Podinovskaia, M, Todd, J, McAdam, K, Blackwell, J, Kwiatkowski, D, Newport, M
格式: Journal article
语言:English
出版: 2004