Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

OBJECTIVES: Osteoarthritis (OA) is the most prevalent form of arthritis and accounts for substantial morbidity and disability, particularly in older people. It is characterised by changes in joint structure, including degeneration of the articular cartilage, and its aetiology is multifactorial with...

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Bibliografiske detaljer
Main Authors: Evangelou, E, Valdes, A, Kerkhof, H, Styrkarsdottir, U, Zhu, Y, Meulenbelt, I, Lories, R, Karassa, F, Tylzanowski, P, Bos, S, Akune, T, Arden, N, Carr, A, Chapman, K, Cupples, L, Dai, J, Deloukas, P, Doherty, M, Doherty, S, Engstrom, G, Gonzalez, A, Halldorsson, B, Hammond, C, Hart, D, Helgadottir, H
Format: Journal article
Sprog:English
Udgivet: 2011