Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2).

Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2).

Using the human hepatoma cell line Hep G2, we have studied a possible role of protein kinase C (PKC) activity for regulation of erythropoietin (EPO) production. During a 72-h incubation, EPO production by the cells was stimulated sevenfold by exposure to low oxygen tension (1%) and threefold by expo...

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Bibliographic Details
Main Authors:	Kurtz, A, Eckardt, K, Pugh, C, Corvol, P, Fabbro, D, Ratcliffe, P
Format:	Journal article
Language:	English
Published:	1992

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