Phorbol ester inhibits erythropoietin production in human hepatoma cells (Hep G2).
Using the human hepatoma cell line Hep G2, we have studied a possible role of protein kinase C (PKC) activity for regulation of erythropoietin (EPO) production. During a 72-h incubation, EPO production by the cells was stimulated sevenfold by exposure to low oxygen tension (1%) and threefold by expo...
主要な著者: | Kurtz, A, Eckardt, K, Pugh, C, Corvol, P, Fabbro, D, Ratcliffe, P |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1992
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