Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases.

The matrix metalloproteinase (MMP) family has been implicated in the process of a variety of diseases such as arthritis, atherosclerosis, and tumor cell metastasis. To study the mechanisms of MMP action on collagenous substrates, we have constructed homotrimeric triple-helical peptide (THP) models o...

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Bibliographic Details
Main Authors: Lauer-Fields, J, Tuzinski, K, Shimokawa, K, Nagase, H, Fields, G
Format: Journal article
Language:English
Published: 2000