Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases.
The matrix metalloproteinase (MMP) family has been implicated in the process of a variety of diseases such as arthritis, atherosclerosis, and tumor cell metastasis. To study the mechanisms of MMP action on collagenous substrates, we have constructed homotrimeric triple-helical peptide (THP) models o...
Main Authors: | Lauer-Fields, J, Tuzinski, K, Shimokawa, K, Nagase, H, Fields, G |
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Format: | Journal article |
Language: | English |
Published: |
2000
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