Selective impairment of platelet activation to collagen in the absence of GATA1.

Defects in the X-linked DNA-binding megakaryocyte transcription factor GATA1 cause thrombocytopenia and abnormal platelet function. However, detailed studies of GATA1 function in platelet activation are lacking. Here, we studied platelets from GATA1-deficient mice and from a male patient (S14) with...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Hughan, S, Senis, Y, Best, D, Thomas, A, Frampton, J, Vyas, P, Watson, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2005