Selective impairment of platelet activation to collagen in the absence of GATA1.
Defects in the X-linked DNA-binding megakaryocyte transcription factor GATA1 cause thrombocytopenia and abnormal platelet function. However, detailed studies of GATA1 function in platelet activation are lacking. Here, we studied platelets from GATA1-deficient mice and from a male patient (S14) with...
Päätekijät: | Hughan, S, Senis, Y, Best, D, Thomas, A, Frampton, J, Vyas, P, Watson, S |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2005
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