Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation.

Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation.

The transcription factor GATA1 coordinates timely activation and repression of megakaryocyte gene expression. Loss of GATA1 function results in excessive megakaryocyte proliferation and disordered terminal platelet maturation, leading to thrombocytopenia and leukemia in patients. The mechanisms by w...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Hamlett, I, Draper, J, Strouboulis, J, Iborra, F, Porcher, C, Vyas, P
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2008

Những quyển sách tương tự

GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1
Bằng: Kuhl, C, et al.
Được phát hành: (2005)

GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1.
Bằng: Kuhl, C, et al.
Được phát hành: (2005)

The bHLH protein SCL/Tal-l interacts with the co-repressor ETO-2 in erythroid cells and megakaryocytes.
Bằng: Schuh, A, et al.
Được phát hành: (2005)

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay
Bằng: Juban, G, et al.
Được phát hành: (2020)

ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.
Bằng: Schuh, A, et al.
Được phát hành: (2005)

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay
Bằng: Gaëtan Juban, et al.
Được phát hành: (2020-06-01)

Characterization of a megakaryocyte-specific enhancer of the key hemopoietic transcription factor GATA1
Bằng: Guyot, B, et al.
Được phát hành: (2005)

Characterization of a megakaryocyte-specific enhancer of the key hemopoietic transcription factor GATA1.
Bằng: Guyot, B, et al.
Được phát hành: (2006)

c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation
Bằng: García, P, et al.
Được phát hành: (2011)

c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation.
Bằng: García, P, et al.
Được phát hành: (2011)

Cross-talk between c-Myb and GATA-1 regulates the entry into megakaryocyte differentiation
Bằng: Berlanga, O, et al.
Được phát hành: (2007)

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.
Bằng: John Timothy Caldwell, et al.
Được phát hành: (2013-01-01)

Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment.
Bằng: Marjolein Meinders, et al.
Được phát hành: (2016-01-01)

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
Bằng: Mancini, E, et al.
Được phát hành: (2012)

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors.
Bằng: Mancini, E, et al.
Được phát hành: (2012)

The abundance of the short GATA1 isoform affects megakaryocyte differentiation and leukemic predisposition in mice
Bằng: Daishi Ishihara, et al.
Được phát hành: (2024-02-01)

Hematopoietic regulation of transcription factor GATA1 and mutations causing hereditary erythroid and megakaryocytic disorders
Bằng: Biying DING, et al.
Được phát hành: (2023-01-01)

A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.
Bằng: Ana C Xavier, et al.
Được phát hành: (2011-01-01)

Characterisation and comparison of the human and mouse GATA-1 transcriptional domain.
Bằng: Vyas, P, et al.
Được phát hành: (2003)

Regulation of Gata1 Expression by HS+3 5
Bằng: Draper, J, et al.
Được phát hành: (2010)

Regulation of Gata1 Expression by HS+3.5
Bằng: Draper, J, et al.
Được phát hành: (2010)

Type 1 inositol polyphosphate-4-phosphatase influences growth of primary megakaryocytes and other cell types and is differentially expressed in the absence of GATA-1.
Bằng: Vyas, P, et al.
Được phát hành: (1999)

hGATA1 Under the Control of a μLCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1low Mutation in Mice
Bằng: Fabrizio Martelli, et al.
Được phát hành: (2021-10-01)

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model
Bằng: Brahim Arkoun, et al.
Được phát hành: (2023-04-01)

Establishment of an ES cell-derived murine megakaryocytic cell line, MKD1, with features of primary megakaryocyte progenitors.
Bằng: Chagraoui, H, et al.
Được phát hành: (2012)

Establishment of an ES cell-derived murine megakaryocytic cell line, MKD1, with features of primary megakaryocyte progenitors.
Bằng: Hedia Chagraoui, et al.
Được phát hành: (2012-01-01)

Transcriptional regulation of GATA1
Bằng: Drissen, R, et al.
Được phát hành: (2007)

Megakaryocyte cultures in the chronic phase and in the blast crisis of chronic myeloid leukaemia: studies on the differentiation of the megakaryocyte progenitors and on the maturation of megakaryocytes in vitro.
Bằng: Vainchenker, W, et al.
Được phát hành: (1982)

Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation.
Bằng: Guyot, B, et al.
Được phát hành: (2004)

The oncoprotein SCL/Tal-1 associates with the co-repressor ETO-2 in multiprotein complexes in erythroid cells and megalkaryocytes.
Bằng: Schuh, A, et al.
Được phát hành: (2004)

Regulation of the human thromboxane A2 receptor gene by Sp1, Egr1, NF-E2, GATA-1, and Ets-1 in megakaryocytes
Bằng: AnneMarie M. Gannon, et al.
Được phát hành: (2008-12-01)

Characterization of distinct GATA-1 complexes in erythroid cells.
Bằng: Rodriguez, P, et al.
Được phát hành: (2005)

Down syndrome-related transient abnormal myelopoiesis is attributed to a specific erythro-megakaryocytic subpopulation with <i>GATA1</i> mutation
Bằng: Yoko Nishinaka-Arai, et al.
Được phát hành: (2020-04-01)

Composition and synthesis of glycolipids in megakaryocytes and platelets: differences in synthesis in megakaryocytes at different stages of maturation
Bằng: PK Schick, et al.
Được phát hành: (1990-09-01)

Impact of mutant haemopoietic transcription factor GATA1s on haemopoiesis
Bằng: Vyas, P, et al.
Được phát hành: (2017)

Megakaryocyte
Bằng: Paulo Augusto Achucarro Silveira, et al.
Được phát hành: (2011-06-01)

Interactions of periodontal pathogens with megakaryocytic cells and platelets
Bằng: A.M. Andrews, et al.
Được phát hành: (2017-05-01)

Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis-element identification.
Bằng: Valverde-Garduno, V, et al.
Được phát hành: (2004)

Characterization of adhesive interactions between human endothelial cells and megakaryocytes
Bằng: Avraham, H, et al.
Được phát hành: (1993)

Lineage-specific transcriptional regulation of GATA1 is dependent on lineage-specific utilisation of multiple cis-elements and haematopoietic transcription factors.
Bằng: Vyas, P, et al.
Được phát hành: (2004)