Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.

Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.

Effects of extracellularly applied ATP (added as disodium salt) on stimulus-secretion coupling were investigated in clonal insulin-producing RINm5F cells. Cytoplasmic free Ca2+ concentration [( Ca2+]i), electrical activity, membrane potential, formation of InsP3 and insulin release were measured. Ad...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Arkhammar, P, Hallberg, A, Kindmark, H, Nilsson, T, Rorsman, P, Berggren, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1990

Παρόμοια τεκμήρια

Interaction with the inositol 1,4,5-trisphosphate receptor promotes Ca2+ sequestration in permeabilised insulin-secreting cells.
ανά: Islam, MS, κ.ά.
Έκδοση: (1991)

Voltage-activated Na+ currents and their suppression by phorbol ester in clonal insulin-producing RINm5F cells.
ανά: Rorsman, P, κ.ά.
Έκδοση: (1986)

Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells.
ανά: Ammälä, C, κ.ά.
Έκδοση: (1991)

Inositol 1,4,5-trisphosphate receptors in the heart.
ανά: Mackenzie, L, κ.ά.
Έκδοση: (2004)

Inositol 1,4,5-trisphosphate receptors in the heart
ανά: LAUREN MACKENZIE, κ.ά.
Έκδοση: (2004-01-01)

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors
ανά: Rossi, A, κ.ά.
Έκδοση: (2010)

Ca2+-Dependent Inositol 1,4,5-Trisphosphate and Nitric Oxide Signaling in Cerebellar Neurons
ανά: Masamitsu Iino
Έκδοση: (2006-01-01)

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca<sup>2+ </sup>mobilization
ανά: Morales-Tlalpan Verónica, κ.ά.
Έκδοση: (2008-12-01)

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.
ανά: Chen, R, κ.ά.
Έκδοση: (2004)

Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca2+ signaling
ανά: Eva Sammels, κ.ά.
Έκδοση: (2010-11-01)

Role of the inositol 1,4,5-trisphosphate receptor/Ca<sup>2+</sup>-release channel in autophagy
ανά: Parys Jan B, κ.ά.
Έκδοση: (2012-07-01)

Synthesis of novel D-myo-inositol 1,4,5-trisphosphate derivatives as molecular probes for Ca2+signaling
ανά: Conway, S, κ.ά.
Έκδοση: (2008)

Measurements of cytoplasmic free Ca2+ concentration in human pancreatic islets and insulinoma cells.
ανά: Kindmark, H, κ.ά.
Έκδοση: (1991)

Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor
ανά: Ye, Y, κ.ά.
Έκδοση: (2011)

Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor.
ανά: Keddie, N, κ.ά.
Έκδοση: (2011)

Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
ανά: Sjöholm, A, κ.ά.
Έκδοση: (1993)

Design and synthesis of myo-inositol (1,4,5)-trisphosphate receptor antagonists
ανά: Ye, Y
Έκδοση: (2013)

The synthesis of membrane permeant derivatives of myo-inositol 1,4,5-trisphosphate
ανά: Conway, S, κ.ά.
Έκδοση: (2006)

Inositol 1,4,5‐trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle
ανά: Muneaki Hashimoto, κ.ά.
Έκδοση: (2016-12-01)

EVIDENCE FOR A DISTURBED METABOLISM OF GLUCOSE IN THE CLONAL B-CELL LINE RINM5F
ανά: Rorsman, P, κ.ά.
Έκδοση: (1983)

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.
ανά: Arkhammar, P, κ.ά.
Έκδοση: (1987)

Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca2+ channels and activation of store-operated Ca2+ entry
ανά: Lara E. Terry, κ.ά.
Έκδοση: (2022-12-01)

Endogenously bound calmodulin is essential for the function of the inositol 1,4,5-trisphosphate receptor.
ανά: Kasri, N, κ.ά.
Έκδοση: (2006)

Inositol 1,4,5- trisphosphate receptor function in Drosophila insulin producing cells.
ανά: Neha Agrawal, κ.ά.
Έκδοση: (2009-08-01)

Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye.
ανά: Takaaki Inaba, κ.ά.
Έκδοση: (2014-01-01)

Decreased Inositol 1,4,5-Trisphosphate Content in Pathogen-Challenged Soybean Cells
ανά: Toshiro Shigaki, κ.ά.
Έκδοση: (2000-05-01)

Inositol 1,4,5-trisphosphate receptor 1 is essential to spinocerebellar ataxia modeling
ανά: Sherry-Ann eBrown, κ.ά.
Έκδοση: (2015-01-01)

The Clustering of Inositol 1,4,5-Trisphosphate (IP3) Receptors Is Triggered by IP3 Binding and Facilitated by Depletion of the Ca2+ Store
ανά: Yosuke Tojyo, κ.ά.
Έκδοση: (2008-01-01)

STIM1 positively regulates the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor in bovine aortic endothelial cells.
ανά: Éric Béliveau, κ.ά.
Έκδοση: (2014-01-01)

MEMBRANE-POTENTIAL, TRANSMEMBRANE CA-45 FLUXES, CYTOPLASMIC FREE CA-2+ CONCENTRATION ([CA-2+]I) AND INSULIN RELEASE BY TRANSPLANTABLE RAT INSULINOMA CELLS
ανά: Flatt, P, κ.ά.
Έκδοση: (1988)

Intracellular pH and the stimulus-secretion coupling in insulin-producing RINm5F cells.
ανά: Juntti-Berggren, L, κ.ά.
Έκδοση: (1992)

Inositol adenophostin: convergent synthesis of a potent agonist of D-myo-inositol 1,4,5-trisphosphate receptors
ανά: Su, X, κ.ά.
Έκδοση: (2020)

Inositol Adenophostin: Convergent Synthesis of a Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors
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Έκδοση: (2020-10-01)

Inositol 1,4,5-trisphosphate signalling regulates the avoidance response to nose touch in Caenorhabditis elegans.
ανά: Denise S Walker, κ.ά.
Έκδοση: (2009-09-01)

Inositol 1,4,5-trisphosphate-induced Ca<sup>2+ </sup>signalling is involved in estradiol-induced breast cancer epithelial cell growth
ανά: Matifat Fabrice, κ.ά.
Έκδοση: (2010-06-01)

Evidence for the existence of secretory granule (dense-core vesicle)-based inositol 1,4,5-trisphosphate-dependent Ca2+ signaling system in astrocytes.
ανά: Yong Suk Hur, κ.ά.
Έκδοση: (2010-01-01)

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ανά: Tao Xiong, κ.ά.
Έκδοση: (2024-04-01)

Apical localization of inositol 1,4,5-trisphosphate receptors is independent of extended synaptotagmins in hepatocytes.
ανά: Maria Jimena Amaya, κ.ά.
Έκδοση: (2014-01-01)

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ανά: Feili Yang, κ.ά.
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