Protonation linked equilibria and apparent affinity constants: the thermodynamic profile of the alpha-chymotrypsin-proflavin interaction.

Protonation/deprotonation equilibria are frequently linked to binding processes involving proteins. The presence of these thermodynamically linked equilibria affects the observable thermodynamic parameters of the interaction (K(obs), DeltaH(obs)(0) ). In order to try and elucidate the energetic fact...

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Main Authors: Bruylants, G, Wintjens, R, Looze, Y, Redfield, C, Bartik, K
格式: Journal article
語言:English
出版: 2007