A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977
A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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Summary: | A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step. |
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