A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977
A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step.
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2001
|
_version_ | 1797089005597097984 |
---|---|
author | Dixon, D Ley, S Reynolds, D Chorghade, MS |
author_facet | Dixon, D Ley, S Reynolds, D Chorghade, MS |
author_sort | Dixon, D |
collection | OXFORD |
description | A short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step. |
first_indexed | 2024-03-07T02:58:15Z |
format | Journal article |
id | oxford-uuid:b00cc5ff-5817-4736-8178-9cfe88dcb9c0 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T02:58:15Z |
publishDate | 2001 |
record_format | dspace |
spelling | oxford-uuid:b00cc5ff-5817-4736-8178-9cfe88dcb9c02022-03-27T03:53:43ZA short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b00cc5ff-5817-4736-8178-9cfe88dcb9c0EnglishSymplectic Elements at Oxford2001Dixon, DLey, SReynolds, DChorghade, MSA short and efficient synthesis of the potent 5-lipoxygenase inhibitor CMI-977 has been accomplished, utilising an oxygen to carbon rearrangement of an anomerically linked alkynyl stannane tetrahydrofuranyl ether derivative as the key step. |
spellingShingle | Dixon, D Ley, S Reynolds, D Chorghade, MS A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title_full | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title_fullStr | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title_full_unstemmed | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title_short | A short and efficient stereoselective synthesis of the potent 5-lipoxygenase inhibitor, CMI-977 |
title_sort | short and efficient stereoselective synthesis of the potent 5 lipoxygenase inhibitor cmi 977 |
work_keys_str_mv | AT dixond ashortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT leys ashortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT reynoldsd ashortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT chorghadems ashortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT dixond shortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT leys shortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT reynoldsd shortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 AT chorghadems shortandefficientstereoselectivesynthesisofthepotent5lipoxygenaseinhibitorcmi977 |