Conformational dynamics of helix S6 from Shaker potassium channel: simulation studies.
Prolines in transmembrane (TM) alpha-helices are believed to play an important structural and/or functional role in membrane proteins. At a structural level a proline residue distorts alpha-helical structure due to the loss of at least one stabilizing backbone hydrogen bond, and introduces flexibili...
Main Authors: | Bright, J, Shrivastava, I, Cordes, F, Sansom, MS |
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Format: | Journal article |
Language: | English |
Published: |
2002
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