Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development
<p style="text-align:justify;"><b>BACKGROUND:</b> Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. A comprehensive simulati...
Main Authors: | Zaloumis, S, Humberstone, A, Charman, S, Price, R, Moehrle, J, Gamo-Benito, J, McCaw, J, Jamsen, K, Smith, K, Simpson, J |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2012
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