Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development

<p style="text-align:justify;"><b>BACKGROUND:</b> Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. A comprehensive simulati...

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Bibliographic Details
Main Authors: Zaloumis, S, Humberstone, A, Charman, S, Price, R, Moehrle, J, Gamo-Benito, J, McCaw, J, Jamsen, K, Smith, K, Simpson, J
Format: Journal article
Language:English
Published: BioMed Central 2012