Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine.
Addition of N-(2-chloroethylidene)- tert-butylsulfinamide to organocerium reagents in DMPU/THF (1:10) at -78 degrees C followed by warming to 25 degrees C provides terminal N-tert-butylsulfinyl aziridines in good yields (63-92%, nine examples) and diastereomeric ratios (85:15- >99:1).
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1797089080707645440 |
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| author | Hodgson, D Kloesges, J Evans, B |
| author_facet | Hodgson, D Kloesges, J Evans, B |
| author_sort | Hodgson, D |
| collection | OXFORD |
| description | Addition of N-(2-chloroethylidene)- tert-butylsulfinamide to organocerium reagents in DMPU/THF (1:10) at -78 degrees C followed by warming to 25 degrees C provides terminal N-tert-butylsulfinyl aziridines in good yields (63-92%, nine examples) and diastereomeric ratios (85:15- >99:1). |
| first_indexed | 2024-03-07T02:59:21Z |
| format | Journal article |
| id | oxford-uuid:b069ff54-fbec-4d46-a944-c64c37c38591 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:59:21Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:b069ff54-fbec-4d46-a944-c64c37c385912022-03-27T03:56:19ZAsymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b069ff54-fbec-4d46-a944-c64c37c38591EnglishSymplectic Elements at Oxford2008Hodgson, DKloesges, JEvans, BAddition of N-(2-chloroethylidene)- tert-butylsulfinamide to organocerium reagents in DMPU/THF (1:10) at -78 degrees C followed by warming to 25 degrees C provides terminal N-tert-butylsulfinyl aziridines in good yields (63-92%, nine examples) and diastereomeric ratios (85:15- >99:1). |
| spellingShingle | Hodgson, D Kloesges, J Evans, B Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title | Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title_full | Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title_fullStr | Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title_full_unstemmed | Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title_short | Asymmetric synthesis of terminal N-tert-butylsulfinyl aziridines from organoceriums and an alpha-chloroimine. |
| title_sort | asymmetric synthesis of terminal n tert butylsulfinyl aziridines from organoceriums and an alpha chloroimine |
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