Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

BACKGROUND: Pulmonary hypertension is a fatal disease characterized by vasoconstriction and vascular remodeling. Loss of endothelial nitric oxide bioavailability is implicated in pulmonary hypertension pathogenesis. Recent evidence suggests that the cofactor tetrahydrobiopterin (BH4) is an importan...

书目详细资料
Main Authors:	Khoo, J, Zhao, L, Alp, N, Bendall, J, Nicoli, T, Rockett, K, Wilkins, MR, Channon, K
格式:	Journal article
语言:	English
出版:	2005

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