A conservative method of testing whether combination analgesics produce additive or synergistic effects using evidence from acute pain and migraine.

A conservative method of testing whether combination analgesics produce additive or synergistic effects using evidence from acute pain and migraine.

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Fixed-dose combination analgesics are used widely, and available both on prescription and over-the-counter. Combination drugs should provide more analgesia than with any single drug in the combination, but there is no evidence in humans about whether oral combinations have just additive effects, or...

書誌詳細
主要な著者:	Moore, R, Derry, C, Derry, S, Straube, S, McQuay, H
フォーマット:	Journal article
言語:	English
出版事項:	2012

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