Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.

Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q.

Myelodysplastic syndromes (MDS) are characterized by abnormal and dysplastic maturation of all blood lineages. Even though epigenetic alterations have been seen in MDS marrow progenitors, very little is known about the molecular alterations in dysplastic peripheral blood cells. We analyzed the methy...

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Main Authors: Zhou, L, Opalinska, J, Sohal, D, Yu, Y, Mo, Y, Bhagat, T, Abdel-Wahab, O, Fazzari, M, Figueroa, M, Alencar, C, Zhang, J, Kambhampati, S, Parmar, S, Nischal, S, Hueck, C, Suzuki, M, Freidman, E, Pellagatti, A, Boultwood, J, Steidl, U, Sauthararajah, Y, Yajnik, V, McMahon, C, Gore, S, Platanias, L
格式: Journal article
语言:English
出版: 2011

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