Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease
The Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a data-driven, comprehensive, psychometrically sound, rating scale for assessing symptoms and functional ability in prodromal and early Huntington...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2011
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| _version_ | 1826310334272503808 |
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| author | Vaccarino, A Sills, T Anderson, K Biglan, K Borowsky, B Giuliano, J Guttman, M Ho, A Kennard, C Kupchak, P Landwehrmeyer, G Michell, A Paulsen, J Reilmann, R Van Kammen, D Warner, J Evans, K |
| author_facet | Vaccarino, A Sills, T Anderson, K Biglan, K Borowsky, B Giuliano, J Guttman, M Ho, A Kennard, C Kupchak, P Landwehrmeyer, G Michell, A Paulsen, J Reilmann, R Van Kammen, D Warner, J Evans, K |
| author_sort | Vaccarino, A |
| collection | OXFORD |
| description | The Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a data-driven, comprehensive, psychometrically sound, rating scale for assessing symptoms and functional ability in prodromal and early Huntington disease (HD) gene expansion carriers. The process involves input from numerous sources to identify relevant symptom domains, including HD individuals, caregivers, and experts from a variety of fields, as well as knowledge gained from the analysis of data from ongoing large-scale studies in HD using existing clinical scales. This is an iterative process in which an ongoing series of field tests in prodromal (prHD) and early HD individuals provides the team with data on which to make decisions regarding which questions should undergo further development or testing and which should be excluded. We report here the development and assessment of the first iteration of interview questions aimed to assess functional impact of motor manifestations in prHD and early HD individuals. |
| first_indexed | 2024-03-07T07:50:23Z |
| format | Journal article |
| id | oxford-uuid:b09b0d51-f253-4ba8-b0d8-ed2d5a35a32c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:50:23Z |
| publishDate | 2011 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | oxford-uuid:b09b0d51-f253-4ba8-b0d8-ed2d5a35a32c2023-07-05T14:11:21ZAssessment of motor symptoms and functional impact in prodromal and early Huntington DiseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b09b0d51-f253-4ba8-b0d8-ed2d5a35a32cEnglishSymplectic Elements at OxfordPublic Library of Science2011Vaccarino, ASills, TAnderson, KBiglan, KBorowsky, BGiuliano, JGuttman, MHo, AKennard, CKupchak, PLandwehrmeyer, GMichell, APaulsen, JReilmann, RVan Kammen, DWarner, JEvans, KThe Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a data-driven, comprehensive, psychometrically sound, rating scale for assessing symptoms and functional ability in prodromal and early Huntington disease (HD) gene expansion carriers. The process involves input from numerous sources to identify relevant symptom domains, including HD individuals, caregivers, and experts from a variety of fields, as well as knowledge gained from the analysis of data from ongoing large-scale studies in HD using existing clinical scales. This is an iterative process in which an ongoing series of field tests in prodromal (prHD) and early HD individuals provides the team with data on which to make decisions regarding which questions should undergo further development or testing and which should be excluded. We report here the development and assessment of the first iteration of interview questions aimed to assess functional impact of motor manifestations in prHD and early HD individuals. |
| spellingShingle | Vaccarino, A Sills, T Anderson, K Biglan, K Borowsky, B Giuliano, J Guttman, M Ho, A Kennard, C Kupchak, P Landwehrmeyer, G Michell, A Paulsen, J Reilmann, R Van Kammen, D Warner, J Evans, K Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title | Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title_full | Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title_fullStr | Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title_full_unstemmed | Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title_short | Assessment of motor symptoms and functional impact in prodromal and early Huntington Disease |
| title_sort | assessment of motor symptoms and functional impact in prodromal and early huntington disease |
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