The Cell Physiology of Biphasic Insulin Secretion.

Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of sec...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Rorsman, P, Eliasson, L, Renström, E, Gromada, J, Barg, S, Göpel, S
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2000
Тодорхойлолт
Тойм:Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of secretory granules and the implications for diabetes.