Cancer and cardiovascular disease after vasectomy: an epidemiological database study.
OBJECTIVE: To determine whether vasectomy is associated with an increased long-term risk of cancer or cardiovascular disease. DESIGN: Analysis of database of linked statistical records of hospital admissions and deaths. SETTING: Health region in southern England. PATIENT(S): Men aged 20-59 years wh...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2005
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| _version_ | 1826291484023848960 |
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| author | Goldacre, M Wotton, C Seagroatt, V Yeates, D |
| author_facet | Goldacre, M Wotton, C Seagroatt, V Yeates, D |
| author_sort | Goldacre, M |
| collection | OXFORD |
| description | OBJECTIVE: To determine whether vasectomy is associated with an increased long-term risk of cancer or cardiovascular disease. DESIGN: Analysis of database of linked statistical records of hospital admissions and deaths. SETTING: Health region in southern England. PATIENT(S): Men aged 20-59 years who were admitted to a hospital for vasectomy. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Rates of cancer and cardiovascular disease compared with the corresponding rates in a reference cohort, expressed as a rate ratio. RESULT(S): We found no elevation of risk, after vasectomy, of prostate cancer (rate ratio 0.74, 95% confidence interval [CI] 0.45-1.14) or other cancers. The rate ratio for coronary heart disease overall after vasectomy was 0.95 (95% CI 0.88-1.02); and the rate ratio > or =20 years after vasectomy was 0.98 (95% CI 0.80-1.19). CONCLUSION(S): Our findings add to the evidence that vasectomy is not associated with an increase in the long-term risk of these diseases. |
| first_indexed | 2024-03-07T03:00:04Z |
| format | Journal article |
| id | oxford-uuid:b0ab9122-da3d-4736-87c7-9fadff185088 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:00:04Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:b0ab9122-da3d-4736-87c7-9fadff1850882022-03-27T03:58:06ZCancer and cardiovascular disease after vasectomy: an epidemiological database study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b0ab9122-da3d-4736-87c7-9fadff185088EnglishSymplectic Elements at Oxford2005Goldacre, MWotton, CSeagroatt, VYeates, D OBJECTIVE: To determine whether vasectomy is associated with an increased long-term risk of cancer or cardiovascular disease. DESIGN: Analysis of database of linked statistical records of hospital admissions and deaths. SETTING: Health region in southern England. PATIENT(S): Men aged 20-59 years who were admitted to a hospital for vasectomy. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Rates of cancer and cardiovascular disease compared with the corresponding rates in a reference cohort, expressed as a rate ratio. RESULT(S): We found no elevation of risk, after vasectomy, of prostate cancer (rate ratio 0.74, 95% confidence interval [CI] 0.45-1.14) or other cancers. The rate ratio for coronary heart disease overall after vasectomy was 0.95 (95% CI 0.88-1.02); and the rate ratio > or =20 years after vasectomy was 0.98 (95% CI 0.80-1.19). CONCLUSION(S): Our findings add to the evidence that vasectomy is not associated with an increase in the long-term risk of these diseases. |
| spellingShingle | Goldacre, M Wotton, C Seagroatt, V Yeates, D Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title | Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title_full | Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title_fullStr | Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title_full_unstemmed | Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title_short | Cancer and cardiovascular disease after vasectomy: an epidemiological database study. |
| title_sort | cancer and cardiovascular disease after vasectomy an epidemiological database study |
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