The neuroprotective effect of erythropoietin in docetaxel-induced peripheral neuropathy causes no reduction of antitumor activity in 13762 adenocarcinoma-bearing rats.
Taxanes, including docetaxel (DOCE), are severely neurotoxic, causing disabling peripheral neuropathy. Co-treatment with neuroprotective agents has been proposed to prevent or reverse this. Besides its hemopoietic effects, erythropoietin (EPO) has neuroprotective and neurotrophic properties and when...
主要な著者: | Cervellini, I, Bello, E, Frapolli, R, Porretta-Serapiglia, C, Oggioni, N, Canta, A, Lombardi, R, Camozzi, F, Roglio, I, Melcangi, R, D'incalci, M, Lauria, G, Ghezzi, P, Cavaletti, G, Bianchi, R |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2010
|
類似資料
-
Docetaxel-induced peripheral neuropathy: protective effects of dihydroprogesterone and progesterone in an experimental model.
著者:: Roglio, I, 等
出版事項: (2009) -
Beneficial effects of PKF275-055, a novel, selective, orally bioavailable, long-acting dipeptidyl peptidase IV inhibitor in streptozotocin-induced diabetic peripheral neuropathy.
著者:: Bianchi, R, 等
出版事項: (2012) -
Experimental epothilone B neurotoxicity: results of in vitro and in vivo studies.
著者:: Chiorazzi, A, 等
出版事項: (2009) -
Experimental epothilone B neurotoxicity: Results of in vitro and in vivo studies
著者:: Alessia Chiorazzi, 等
出版事項: (2009-08-01) -
Erythropoietin does not affect TNF and IL-6 production directly.
著者:: Cervellini, I, 等
出版事項: (2013)