The neuroprotective effect of erythropoietin in docetaxel-induced peripheral neuropathy causes no reduction of antitumor activity in 13762 adenocarcinoma-bearing rats.

Taxanes, including docetaxel (DOCE), are severely neurotoxic, causing disabling peripheral neuropathy. Co-treatment with neuroprotective agents has been proposed to prevent or reverse this. Besides its hemopoietic effects, erythropoietin (EPO) has neuroprotective and neurotrophic properties and when...

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書目詳細資料
Main Authors: Cervellini, I, Bello, E, Frapolli, R, Porretta-Serapiglia, C, Oggioni, N, Canta, A, Lombardi, R, Camozzi, F, Roglio, I, Melcangi, R, D'incalci, M, Lauria, G, Ghezzi, P, Cavaletti, G, Bianchi, R
格式: Journal article
語言:English
出版: 2010

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