The neuroprotective effect of erythropoietin in docetaxel-induced peripheral neuropathy causes no reduction of antitumor activity in 13762 adenocarcinoma-bearing rats.

Taxanes, including docetaxel (DOCE), are severely neurotoxic, causing disabling peripheral neuropathy. Co-treatment with neuroprotective agents has been proposed to prevent or reverse this. Besides its hemopoietic effects, erythropoietin (EPO) has neuroprotective and neurotrophic properties and when...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Cervellini, I, Bello, E, Frapolli, R, Porretta-Serapiglia, C, Oggioni, N, Canta, A, Lombardi, R, Camozzi, F, Roglio, I, Melcangi, R, D'incalci, M, Lauria, G, Ghezzi, P, Cavaletti, G, Bianchi, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2010