Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.

Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria.

BACKGROUND: The Plasmodium purine salvage enzyme, hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) can protect mice against Plasmodium yoelii pRBC challenge in a T cell-dependent manner and has, therefore, been proposed as a novel vaccine candidate. It is not known whether natural...

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Bibliographic Details
Main Authors: Woodberry, T, Pinzon-Charry, A, Piera, K, Panpisutchai, Y, Engwerda, C, Doolan, D, Salwati, E, Kenangalem, E, Tjitra, E, Price, R, Good, M, Anstey, N
Format: Journal article
Language:English
Published: BioMed Central 2009

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