Disability as an outcome in MS clinical trials.
BACKGROUND: Inferences about long-term effects of therapies in multiple sclerosis (MS) have been based on surrogate markers studied in short-term trials. Preventing progressive disability is the key therapeutic goal but there remains no validated definition for its measurement in a trial context. M...
Hauptverfasser: | Ebers, G, Heigenhauser, L, Daumer, M, Lederer, C, Noseworthy, J |
---|---|
Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2008
|
Ähnliche Einträge
Ähnliche Einträge
-
Measuring disability progression in MS
von: Ebers, G, et al.
Veröffentlicht: (2005) -
Combined MRI lesions and relapses as a surrogate for disability in MS.
von: Ebers, G, et al.
Veröffentlicht: (2012) -
Interrater variability with the Expanded Disability Status Scale (EDSS) and Functional Systems (FS) in a multiple sclerosis clinical trial. The Canadian Cooperation MS Study Group.
von: Noseworthy, J, et al.
Veröffentlicht: (1990) -
Natural history of MS.
von: Ebers, G, et al.
Veröffentlicht: (2008) -
Surrogate endpoints for EDSS worsening in multiple sclerosis: a meta-analytic approach: measuring disability in relapsing-remitting MS.
von: Ebers, G, et al.
Veröffentlicht: (2011)