Crispr-mediated gene activation (CRISPRa) of pp38/pp24 orchestrates events triggering lytic infection in Marek’s disease virus-transformed cell lines

Marek’s disease (MD) is an immunosuppressive and highly contagious lymphoproliferative disease caused by Marek’s disease virus (MDV) in poultry. Lymphoblastoid cell lines (LCLs) generated ex vivo from MD lymphomas are considered excellent models to study virus-host molecular interactions. LCLs mostl...

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Bibliographic Details
Main Authors: Roy, P, Moffat, K, Nair, V, Yao, Y
Format: Journal article
Language:English
Published: MDPI 2021

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