Crispr-mediated gene activation (CRISPRa) of pp38/pp24 orchestrates events triggering lytic infection in Marek’s disease virus-transformed cell lines
Marek’s disease (MD) is an immunosuppressive and highly contagious lymphoproliferative disease caused by Marek’s disease virus (MDV) in poultry. Lymphoblastoid cell lines (LCLs) generated ex vivo from MD lymphomas are considered excellent models to study virus-host molecular interactions. LCLs mostl...
Main Authors: | Roy, P, Moffat, K, Nair, V, Yao, Y |
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Format: | Journal article |
Language: | English |
Published: |
MDPI
2021
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