Tetradecanoylphorbol-13-acetate (TPA) significantly increases AAV2/5 transduction of human neuronal cells in vitro.

Tetradecanoylphorbol-13-acetate (TPA) significantly increases AAV2/5 transduction of human neuronal cells in vitro.

Weitere Versionen anzeigen (1)

Recombinant adeno-associated virus type 2 (AAV2) vectors have shown great promise in current ophthalmology clinical trials targeting gene delivery to the retinal pigment epithelium (RPE). To treat the majority of retinal diseases, however, gene delivery would need to be targeted to photoreceptor neu...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	You, Q, Brown, L, McClements, M, Hankins, M, Maclaren, R
Format:	Journal article
Sprache:	English
Veröffentlicht:	2012

Ähnliche Einträge

Tetradecanoylphorbol-13-acetate (TPA) significantly increases AAV2/5 transduction of human neuronal cells in vitro
von: You, Q, et al.
Veröffentlicht: (2012)

Stimulation of melanogenesis by tetradecanoylphorbol 13-acetate (TPA) in mouse melanocytes and neural crest cells.
von: Prince, S, et al.
Veröffentlicht: (2003)

Suppression of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin inflammation in mice by transduced Tat-Annexin protein
von: Sun Hwa Lee1,#, Dae Won Kim1,#, Seon Ae Eom1, Se-Young Jun1, Meeyoung Park1, Duk-Soo Kim2, Hyung Joo Kwon3, Hyeok Yil Kwon4, Kyu Hyung Han1, Jinseu Park1, Hyun Sook Hwang1, Won Sik Eum1,* & Soo Young Choi1,*
Veröffentlicht: (2012-06-01)

5-Demethyltangeretin is more potent than tangeretin in inhibiting dimethylbenz(a)anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis
von: Nianhan Ma, et al.
Veröffentlicht: (2014-11-01)

Inclusion of the woodchuck hepatitis virus posttranscriptional regulatory element enhances AAV2-driven transduction of mouse and human retina
von: Patrício, M, et al.
Veröffentlicht: (2017)

Inhibitory effect of garcinol against 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumorigenesis in mice
von: Wei-Lun Hung, et al.
Veröffentlicht: (2015-10-01)

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina
von: Maria I. Patrício, et al.
Veröffentlicht: (2017-03-01)

Adeno-associated virus (AAV) dual vector strategies for gene therapy encoding large transgenes
von: McClements, M, et al.
Veröffentlicht: (2017)

Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons
von: Benjamin D. W. Belfort, et al.
Veröffentlicht: (2025-02-01)

Anti-inflammatory activity of Haruan (Channa striatus bloch) cream on 12-O-tetradecanoylphorbol-13-acetate-induced chronic dermatitis in mice model
von: Mohamad Isa, Irma Izani
Veröffentlicht: (2015)

12-<i>O</i>-tetradecanoylphorbol-13-acetate Reduces Activation of Hepatic Stellate Cells by Inhibiting the Hippo Pathway Transcriptional Coactivator YAP
von: Chang Wan Kim, et al.
Veröffentlicht: (2022-12-01)

Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin
von: Wei Wen-Chi, et al.
Veröffentlicht: (2011-12-01)

An AAV capsid increases transduction of striatum and a ChAT promoter allows selective cholinergic neuron transduction
von: Miguel C. Santoscoy, et al.
Veröffentlicht: (2023-06-01)

Differential role of PKC-induced c-Jun in HTLV-1 LTR activation by 12-O-tetradecanoylphorbol-13-acetate in different human T-cell lines.
von: Ammar Abou-Kandil, et al.
Veröffentlicht: (2012-01-01)

Cell-mediated inflammatory response to AAV gene therapy in the retina
von: Chandler, LC, et al.
Veröffentlicht: (2020)

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
von: Hickey, DG, et al.
Veröffentlicht: (2017)

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4<sup>+</sup> T Lymphocytes
von: Cheng-Chieh Tsai, et al.
Veröffentlicht: (2020-06-01)

A custom-made AAV1 variant (AAV1-T593K) enables efficient transduction of Japanese quail neurons in vitro and in vivo
von: Shaden Zoabi, et al.
Veröffentlicht: (2023-03-01)

Is subretinal AAV gene replacement still the only viable treatment option for choroideremia?
von: Han, RC, et al.
Veröffentlicht: (2021)

Successful Transduction with AAV Vectors after Selective Depletion of Anti-AAV Antibodies by Immunoadsorption
von: Alejandro Orlowski, et al.
Veröffentlicht: (2020-03-01)

Promoter orientation within an AAV-CRISPR vector affects Cas9 expression and gene editing efficiency
von: Fry, LE, et al.
Veröffentlicht: (2020)

Preferential transduction of parvalbumin-expressing cortical neurons by AAV-mDLX5/6 vectors
von: Padideh Yazdan-Shahmorad, et al.
Veröffentlicht: (2024-02-01)

AAV11 enables efficient retrograde targeting of projection neurons and enhances astrocyte-directed transduction
von: Zengpeng Han, et al.
Veröffentlicht: (2023-06-01)

An AAV dual vector strategy ameliorates the Stargardt phenotype in adult Abca4−/− mice
von: McClements, ME, et al.
Veröffentlicht: (2018)

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex-vivo
von: De Silva, S, et al.
Veröffentlicht: (2016)

Engineered AAV2.7m8 Serotype Shows Significantly Higher Transduction Efficiency of ARPE-19 and HEK293 Cell Lines Compared to AAV5, AAV8 and AAV9 Serotypes
von: Dzerassa Gurtsieva, et al.
Veröffentlicht: (2024-01-01)

Enhancement of adeno-associated viral (AAV) gene therapy using hydroxychloroquine in murine and human tissues
von: Chandler, L, et al.
Veröffentlicht: (2019)

Impact of vital dyes on cell viability and transduction efficiency of AAV vectors used in retinal gene therapy surgery: an in vitro and in vivo analysis
von: Salvetti, A, et al.
Veröffentlicht: (2017)

Better Targeting, Better Efficiency for Wide-scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B
von: Kasey L Jackson, et al.
Veröffentlicht: (2016-11-01)

Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina
von: Chandler, LC, et al.
Veröffentlicht: (2021)

Comparison of the Transduction Capacity of AAV5 and AAV PHP.eB Serotypes in Hippocampus Astroglia
von: Anastasia Borodinova, et al.
Veröffentlicht: (2023-11-01)

Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors
von: Handa, A, et al.
Veröffentlicht: (2000)

Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors.
von: Handa, A, et al.
Veröffentlicht: (2000)

Assessment of Adipocyte Transduction Using Different AAV Capsid Variants
von: Stanislav Boychenko, et al.
Veröffentlicht: (2024-09-01)

Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction
von: Sanjar Batirovich Madrakhimov, et al.
Veröffentlicht: (2020-06-01)

Role of Essential Metal Ions in AAV Vector-Mediated Transduction
von: Himanshu K. Rambhai, et al.
Veröffentlicht: (2020-09-01)

Polymers for improving the in vivo transduction efficiency of AAV2 vectors.
von: Gilles Moulay, et al.
Veröffentlicht: (2010-12-01)

Praeruptorin B Inhibits 12-O-Tetradecanoylphorbol-13-Acetate–Induced Cell Invasion by Targeting AKT/NF-κB via Matrix Metalloproteinase-2/-9 Expression in Human Cervical Cancer Cells
von: Ching-Yi Hung, et al.
Veröffentlicht: (2019-04-01)

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS
von: Nicholas M. Kanaan, et al.
Veröffentlicht: (2017-09-01)

RNA editing for Usher syndrome using CRISPR-Cas13
von: Fry, LE, et al.
Veröffentlicht: (2020)