Cyclic alkenylsiloxanes: synthesis and application towards incednam
<p>This thesis explores the use of cyclic alkenylsiloxanes in Hiyama cross-coupling reactions for the stereospecific construction of the Z-pentaenyl system of incednam, the aglycon of incednine. The early chapters continue the investigation of the previously developed C6-C13 lynchpin cyclic...
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| Format: | Thesis |
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2016
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| _version_ | 1797089159110721536 |
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| author | Gudmundsson, H |
| author2 | Anderson, E |
| author_facet | Anderson, E Gudmundsson, H |
| author_sort | Gudmundsson, H |
| collection | OXFORD |
| description | <p>This thesis explores the use of cyclic alkenylsiloxanes in Hiyama cross-coupling reactions for the stereospecific construction of the Z-pentaenyl system of incednam, the aglycon of incednine. The early chapters continue the investigation of the previously developed C6-C13 lynchpin cyclic diethyl alkenylsiloxane, accessed by controlled semi-hydrogenation of alkynylsiloxane. Later chapters discuss the development of a novel strategy to access the more reactive cyclic dimethyl alkenylsiloxanes and their application towards the synthesis of incednam.</p> |
| first_indexed | 2024-03-07T03:00:25Z |
| format | Thesis |
| id | oxford-uuid:b0c70071-ffda-44a9-bb14-69b2ded14f63 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T03:00:25Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | oxford-uuid:b0c70071-ffda-44a9-bb14-69b2ded14f632022-03-27T03:58:55ZCyclic alkenylsiloxanes: synthesis and application towards incednamThesishttp://purl.org/coar/resource_type/c_db06uuid:b0c70071-ffda-44a9-bb14-69b2ded14f63ORA Deposit2016Gudmundsson, HAnderson, E<p>This thesis explores the use of cyclic alkenylsiloxanes in Hiyama cross-coupling reactions for the stereospecific construction of the Z-pentaenyl system of incednam, the aglycon of incednine. The early chapters continue the investigation of the previously developed C6-C13 lynchpin cyclic diethyl alkenylsiloxane, accessed by controlled semi-hydrogenation of alkynylsiloxane. Later chapters discuss the development of a novel strategy to access the more reactive cyclic dimethyl alkenylsiloxanes and their application towards the synthesis of incednam.</p> |
| spellingShingle | Gudmundsson, H Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title | Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title_full | Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title_fullStr | Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title_full_unstemmed | Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title_short | Cyclic alkenylsiloxanes: synthesis and application towards incednam |
| title_sort | cyclic alkenylsiloxanes synthesis and application towards incednam |
| work_keys_str_mv | AT gudmundssonh cyclicalkenylsiloxanessynthesisandapplicationtowardsincednam |