Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness

Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness

Disorders of consciousness (DoC) represent a challenging and complex group of neurological conditions characterised by profound disturbances in consciousness. The current range of treatments for DoC is limited. This has sparked growing interest in developing new treatments, including the use of psyc...

Full description

Bibliographic Details
Main Authors:	Mindlin, I, Herzog, R, Belloli, L, Manasova, D, Monge-Asensio, M, Vohryzek, J, Escrichs, A, Alnagger, N, Núñez, P, Gosseries, O, Kringelbach, ML, Deco, G, Tagliazucchi, E, Naccache, L, Rohaut, B, Sitt, JD, Sanz Perl, Y
Format:	Journal article
Language:	English
Published:	Nature Research 2024

Similar Items

Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness
by: I. Mindlin, et al.
Published: (2024-09-01)

THE LACK OF TEMPORAL BRAIN DYNAMICS ASYMMETRY AS A SIGNATURE OF IMPAIRED CONSCIOUSNESS STATES
by: Elvira G. Guzmán, et al.
Published: (2023-10-01)

Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation
by: Dagnino, PC, et al.
Published: (2024)

Strength-dependent perturbation of whole-brain model working in different regimes reveals the role of fluctuations in brain dynamics.
by: Yonatan Sanz Perl, et al.
Published: (2022-11-01)

Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation.
by: Paulina Clara Dagnino, et al.
Published: (2024-05-01)

Low-dimensional organization of global brain states of reduced consciousness
by: Yonatan Sanz Perl, et al.
Published: (2023-05-01)

Auditory Event-Related “Global Effect” Predicts Recovery of Overt Consciousness
by: Pauline Perez, et al.
Published: (2021-01-01)

Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder
by: Escrichs, A, et al.
Published: (2024)

Distinct dynamic connectivity profiles promote enhanced conscious perception of auditory stimuli
by: Başak Türker, et al.
Published: (2024-07-01)

Unifying turbulent dynamics framework distinguishes different brain states
by: Anira Escrichs, et al.
Published: (2022-06-01)

Turbulent dynamics and whole-brain modeling: toward new clinical applications for traumatic brain injury
by: Noelia Martínez-Molina, et al.
Published: (2024-03-01)

Scaling of whole-brain dynamics reproduced by high-order moments of turbulence indicators
by: Yonatan Sanz Perl, et al.
Published: (2023-09-01)

The INSIDEOUT framework provides precise signatures of the balance of intrinsic and extrinsic dynamics in brain states
by: Gustavo Deco, et al.
Published: (2022-06-01)

The arrow of time of brain signals in cognition: Potential intriguing role of parts of the default mode network
by: Gustavo Deco, et al.
Published: (2023-08-01)

Effects of classic psychedelic drugs on turbulent signatures in brain dynamics
by: Josephine Cruzat, et al.
Published: (2022-01-01)

Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
by: Ane López-González, et al.
Published: (2021-09-01)

Electromagnetic Brain Stimulation in Patients With Disorders of Consciousness
by: Pierre Bourdillon, et al.
Published: (2019-03-01)

The impact of regional heterogeneity in whole-brain dynamics in the presence of oscillations
by: Yonatan Sanz Perl, et al.
Published: (2023-01-01)

Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness
by: Andrea I. Luppi, et al.
Published: (2023-07-01)

The nature of consciousness in anaesthesia
by: Javier Montupil, et al.
Published: (2023-12-01)

Multimodal FDG-PET and EEG assessment improves diagnosis and prognostication of disorders of consciousness
by: Bertrand Hermann, et al.
Published: (2021-01-01)

The evolution of whole-brain turbulent dynamics during recovery from traumatic brain injury
by: Noelia Martínez-Molina, et al.
Published: (2024-02-01)

Ghost Attractors in Spontaneous Brain Activity: Recurrent Excursions Into Functionally-Relevant BOLD Phase-Locking States
by: Jakub Vohryzek, et al.
Published: (2020-04-01)

Whole-Brain Models to Explore Altered States of Consciousness from the Bottom Up
by: Rodrigo Cofré, et al.
Published: (2020-09-01)

What lies underneath: Precise classification of brain states using time-dependent topological structure of dynamics.
by: Fernando Soler-Toscano, et al.
Published: (2022-09-01)

Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans
by: Pablo Castro, et al.
Published: (2024-09-01)

Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition
by: Sebastian Moguilner, et al.
Published: (2024-04-01)

Disruption in structural–functional network repertoire and time-resolved subcortical fronto-temporoparietal connectivity in disorders of consciousness
by: Rajanikant Panda, et al.
Published: (2022-08-01)

Neural mass modeling for the masses: Democratizing access to whole-brain biophysical modeling with FastDMF
by: Rubén Herzog, et al.
Published: (2024-10-01)

Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression
by: Deco, G, et al.
Published: (2024)

Pupil dilation response elicited by violations of auditory regularities is a promising but challenging approach to probe consciousness at the bedside
by: Aude Sangare, et al.
Published: (2023-11-01)

Dynamic sensitivity analysis: Defining personalised strategies to drive brain state transitions via whole brain modelling
by: Jakub Vohryzek, et al.
Published: (2023-01-01)

Modeling regional changes in dynamic stability during sleep and wakefulness
by: Ignacio Perez Ipiña, et al.
Published: (2020-07-01)

Multidimensional cognitive evaluation of patients with disorders of consciousness using EEG: A proof of concept study
by: Claire Sergent, et al.
Published: (2017-01-01)

The Menstrual Cycle Modulates Whole-Brain Turbulent Dynamics
by: Eleonora De Filippi, et al.
Published: (2021-12-01)

Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses
by: Diego Candia-Rivera, et al.
Published: (2023-10-01)

The meditative brain: State and trait changes in harmonic complexity for long-term mindfulness meditators
by: Atasoy, S, et al.
Published: (2023)

Hypnotic Induction of Deafness to Elementary Sounds: An Electroencephalography Case-Study and a Proposed Cognitive and Neural Scenario
by: Esteban Munoz Musat, et al.
Published: (2022-03-01)

Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT)
by: Piccinini, JI, et al.
Published: (2025)

The effect of turbulence in brain dynamics information transfer measured with magnetoencephalography
by: Gustavo Deco, et al.
Published: (2023-04-01)