Effective suppression of HIV-1 replication by cytotoxic T lymphocytes specific for pol epitopes in conserved mosaic vaccine immunogens

Effective suppression of HIV-1 replication by cytotoxic T lymphocytes specific for pol epitopes in conserved mosaic vaccine immunogens

Cytotoxic T lymphocytes (CTLs) with strong abilities to suppress HIV-1 replication and recognize circulating HIV-1 could be key for both HIV-1 cure and prophylaxis. We recently designed conserved mosaic T-cell vaccine immunogens tHIVconsvX composed of 6 Gag and Pol regions. Since the tHIVconsvX vacc...

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Những tác giả chính:	Zou, C, Murakoshi, H, Kuse, N, Akahoshi, T, Chikata, T, Gatanaga, H, Oka, S, Hanke, T, Takiguchi, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	American Society for Microbiology 2019

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