Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells

Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells

MT1-MMP plays a crucial role in promoting the cellular invasion of cancer cells by degrading the extracellular matrix to create a path for migration. During this process, its localization at the leading edge of migrating cells is critical, and it is achieved by targeted transport of MT1-MMP-containi...

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Bibliografiska uppgifter
Huvudupphovsmän:	Gifford, V, Woskowicz, A, Ito, N, Balint, S, Lagerholm, B, Dustin, M, Itoh, Y
Materialtyp:	Journal article
Språk:	English
Publicerad:	Elsevier 2022

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