Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.

Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer.

Tobacco smoking is the most important and well-established bladder cancer risk factor and a rich source of chemical carcinogens and reactive oxygen species that can induce damage to DNA in urothelial cells. Therefore, common variation in DNA repair genes might modify bladder cancer risk. In this stu...

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Hlavní autoři: Stern, M, Lin, J, Figueroa, J, Kelsey, K, Kiltie, A, Yuan, J, Matullo, G, Fletcher, T, Benhamou, S, Taylor, J, Placidi, D, Zhang, Z, Steineck, G, Rothman, N, Kogevinas, M, Silverman, D, Malats, N, Chanock, S, Wu, X, Karagas, MR, Andrew, A, Nelson, H, Bishop, D, Sak, S, Choudhury, A
Médium: Journal article
Jazyk:English
Vydáno: 2009

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