Toll-like receptor 3 increases antigen-presenting cell responses to a pro-apoptotic stimulus, yet does not contribute to systemic lupus erythematosus genetic susceptibility
<strong>Objectives:</strong> TLR3 mediates skin solar injury by binding nuclear material released from apoptotic keratinocytes, resulting in the production of pro-inflammatory cytokines. Because the TLR3 gene is located in 4q35, a known systemic lupus erythematosus (SLE) susceptibility l...
Main Authors: | De Groof, A, Ducreux, J, Vidal-Bralo, L, Tyteca, D, Galant, C, Marot, L, Coulie, PG, Van den Eynde, BJ, Rodriguez-Martinez, L, Santos, MJ, Suarez, A, Carreira, P, Marchini, M, Gonzàlez, A, Houssiau, FA, Lauwerys, BR |
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Format: | Journal article |
Language: | English |
Published: |
Clinical and Experimental Rheumatology
2020
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