The influence of BRCA1's ubiquitin ligase activity on cell motility

The influence of BRCA1's ubiquitin ligase activity on cell motility

<p>Breast cancer type 1 susceptibility protein (BRCA1) has been established as an important tumour suppressor protein and its loss of function is associated with hereditary breast and ovarian cancer. An emerging body of work suggests that BRCA1 is involved in sporadic cases of breast and ovar...

Descripció completa

Dades bibliogràfiques
Autor principal:	Sengupta, S
Altres autors:	Vaux, D
Format:	Thesis
Idioma:	English
Publicat:	2014
Matèries:	Tumour pathology Cell Biology (see also Plant sciences) Pathology Oncology Mass spectrometry

Ítems similars

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
per: Knowles, H, et al.
Publicat: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
per: Ledaki, I
Publicat: (2013)

Functional analysis of cancer/testis antigens in human cancer
per: Pagotto, A
Publicat: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
per: Schulz, J
Publicat: (2013)

The role of p53 in hypoxia-induced apoptosis
per: Poole, R
Publicat: (2010)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
per: Feldinger, K
Publicat: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
per: Kesoglidou, PX
Publicat: (2012)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
per: Phipps, L
Publicat: (2011)

Studies on HIF hydroxylases
per: Webb, J
Publicat: (2008)

The effect of farnesylated prelamin A accumulation on nuclear morphology and function
per: Goulbourne, C
Publicat: (2011)

Cell stress response and hypoxia in breast cancer
per: Milani, M, et al.
Publicat: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
per: Johnson, J
Publicat: (2011)

Regulation of E2F-1 by methylation and NEDDylation
per: Loftus, S, et al.
Publicat: (2012)

The role of protein kinase C in platelet activation
per: Unsworth, AJ
Publicat: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
per: Grijzenhout, A
Publicat: (2013)

The role of Adaptor Protein 3 in cytotoxic T lymphocytes
per: Wenham, M
Publicat: (2009)

Factors contributing to chondroplasia in degenerate rotator cuff disease
per: Cornell, HR
Publicat: (2011)

The role and regulation of Asterless in the centrosome cycle
per: Novak, ZA
Publicat: (2014)

Towards understanding the mechanism of cohesin loading
per: Dixon, SE
Publicat: (2013)

Functions of conserved centriole proteins in African trypanosomes
per: Scheumann, N
Publicat: (2012)

The role of protein arginine methylation in T-lymphocyte activation
per: Geoghegan, V, et al.
Publicat: (2012)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
per: Peterneva, K
Publicat: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
per: Halstead, J
Publicat: (2013)

The automated analysis and statistical characterisation of subcellular biological images
per: Li, S, et al.
Publicat: (2012)

Regulation and reproductive functions of membrane-bound vesicles secreted by the Drosophila male accessory gland
per: Corrigan, L
Publicat: (2014)

The role of ATF4 in hypoxia-induced cell death in cancer
per: Pike, L, et al.
Publicat: (2011)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
per: Duncan, T
Publicat: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
per: Khan, FF
Publicat: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
per: Portman, N
Publicat: (2011)

Structure-function studies of fibronectin domains in the human endometrium
per: Mok, M, et al.
Publicat: (2008)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
per: Zayer, A
Publicat: (2012)

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis
per: Meireles, A, et al.
Publicat: (2009)

The evolution of eukaryotic cilia
per: Hodges, M, et al.
Publicat: (2011)

The role of Topoisomerase II in replication in mammalian cells
per: Muftic, D
Publicat: (2011)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
per: Moss, J
Publicat: (2011)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
per: Fergusson, J, et al.
Publicat: (2015)

Segmentation of cell clumps for quantitative analysis
per: Li, S
Publicat: (2010)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
per: Gibson, K
Publicat: (2011)

The relation between multilocus population genetics and social evolution theory
per: Gardner, A, et al.
Publicat: (2007)

Synonymous codon usage influences the local protein structure observed
per: Saunders, R, et al.
Publicat: (2010)