The influence of BRCA1's ubiquitin ligase activity on cell motility

The influence of BRCA1's ubiquitin ligase activity on cell motility

<p>Breast cancer type 1 susceptibility protein (BRCA1) has been established as an important tumour suppressor protein and its loss of function is associated with hereditary breast and ovarian cancer. An emerging body of work suggests that BRCA1 is involved in sporadic cases of breast and ovar...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Sengupta, S
Awduron Eraill:	Vaux, D
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2014
Pynciau:	Tumour pathology Cell Biology (see also Plant sciences) Pathology Oncology Mass spectrometry

Eitemau Tebyg

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
gan: Knowles, H, et al.
Cyhoeddwyd: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
gan: Ledaki, I
Cyhoeddwyd: (2013)

Functional analysis of cancer/testis antigens in human cancer
gan: Pagotto, A
Cyhoeddwyd: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
gan: Schulz, J
Cyhoeddwyd: (2013)

The role of p53 in hypoxia-induced apoptosis
gan: Poole, R
Cyhoeddwyd: (2010)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
gan: Feldinger, K
Cyhoeddwyd: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
gan: Kesoglidou, PX
Cyhoeddwyd: (2012)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
gan: Phipps, L
Cyhoeddwyd: (2011)

Studies on HIF hydroxylases
gan: Webb, J
Cyhoeddwyd: (2008)

The effect of farnesylated prelamin A accumulation on nuclear morphology and function
gan: Goulbourne, C
Cyhoeddwyd: (2011)

Cell stress response and hypoxia in breast cancer
gan: Milani, M, et al.
Cyhoeddwyd: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
gan: Johnson, J
Cyhoeddwyd: (2011)

Regulation of E2F-1 by methylation and NEDDylation
gan: Loftus, S, et al.
Cyhoeddwyd: (2012)

The role of protein kinase C in platelet activation
gan: Unsworth, AJ
Cyhoeddwyd: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
gan: Grijzenhout, A
Cyhoeddwyd: (2013)

The role of Adaptor Protein 3 in cytotoxic T lymphocytes
gan: Wenham, M
Cyhoeddwyd: (2009)

Factors contributing to chondroplasia in degenerate rotator cuff disease
gan: Cornell, HR
Cyhoeddwyd: (2011)

The role and regulation of Asterless in the centrosome cycle
gan: Novak, ZA
Cyhoeddwyd: (2014)

Towards understanding the mechanism of cohesin loading
gan: Dixon, SE
Cyhoeddwyd: (2013)

Functions of conserved centriole proteins in African trypanosomes
gan: Scheumann, N
Cyhoeddwyd: (2012)

The role of protein arginine methylation in T-lymphocyte activation
gan: Geoghegan, V, et al.
Cyhoeddwyd: (2012)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
gan: Peterneva, K
Cyhoeddwyd: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
gan: Halstead, J
Cyhoeddwyd: (2013)

The automated analysis and statistical characterisation of subcellular biological images
gan: Li, S, et al.
Cyhoeddwyd: (2012)

Regulation and reproductive functions of membrane-bound vesicles secreted by the Drosophila male accessory gland
gan: Corrigan, L
Cyhoeddwyd: (2014)

The role of ATF4 in hypoxia-induced cell death in cancer
gan: Pike, L, et al.
Cyhoeddwyd: (2011)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
gan: Duncan, T
Cyhoeddwyd: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
gan: Khan, FF
Cyhoeddwyd: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
gan: Portman, N
Cyhoeddwyd: (2011)

Structure-function studies of fibronectin domains in the human endometrium
gan: Mok, M, et al.
Cyhoeddwyd: (2008)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
gan: Zayer, A
Cyhoeddwyd: (2012)

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis
gan: Meireles, A, et al.
Cyhoeddwyd: (2009)

The evolution of eukaryotic cilia
gan: Hodges, M, et al.
Cyhoeddwyd: (2011)

The role of Topoisomerase II in replication in mammalian cells
gan: Muftic, D
Cyhoeddwyd: (2011)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
gan: Moss, J
Cyhoeddwyd: (2011)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
gan: Fergusson, J, et al.
Cyhoeddwyd: (2015)

Segmentation of cell clumps for quantitative analysis
gan: Li, S
Cyhoeddwyd: (2010)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
gan: Gibson, K
Cyhoeddwyd: (2011)

The relation between multilocus population genetics and social evolution theory
gan: Gardner, A, et al.
Cyhoeddwyd: (2007)

Synonymous codon usage influences the local protein structure observed
gan: Saunders, R, et al.
Cyhoeddwyd: (2010)