The influence of BRCA1's ubiquitin ligase activity on cell motility

The influence of BRCA1's ubiquitin ligase activity on cell motility

<p>Breast cancer type 1 susceptibility protein (BRCA1) has been established as an important tumour suppressor protein and its loss of function is associated with hereditary breast and ovarian cancer. An emerging body of work suggests that BRCA1 is involved in sporadic cases of breast and ovar...

Полное описание

Библиографические подробности
Главный автор:	Sengupta, S
Другие авторы:	Vaux, D
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Tumour pathology Cell Biology (see also Plant sciences) Pathology Oncology Mass spectrometry

Схожие документы

Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF
по: Knowles, H, и др.
Опубликовано: (2008)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
по: Ledaki, I
Опубликовано: (2013)

Functional analysis of cancer/testis antigens in human cancer
по: Pagotto, A
Опубликовано: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
по: Schulz, J
Опубликовано: (2013)

The role of p53 in hypoxia-induced apoptosis
по: Poole, R
Опубликовано: (2010)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
по: Feldinger, K
Опубликовано: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
по: Kesoglidou, PX
Опубликовано: (2012)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
по: Phipps, L
Опубликовано: (2011)

Studies on HIF hydroxylases
по: Webb, J
Опубликовано: (2008)

The effect of farnesylated prelamin A accumulation on nuclear morphology and function
по: Goulbourne, C
Опубликовано: (2011)

Cell stress response and hypoxia in breast cancer
по: Milani, M, и др.
Опубликовано: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
по: Johnson, J
Опубликовано: (2011)

Regulation of E2F-1 by methylation and NEDDylation
по: Loftus, S, и др.
Опубликовано: (2012)

The role of protein kinase C in platelet activation
по: Unsworth, AJ
Опубликовано: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
по: Grijzenhout, A
Опубликовано: (2013)

The role of Adaptor Protein 3 in cytotoxic T lymphocytes
по: Wenham, M
Опубликовано: (2009)

Factors contributing to chondroplasia in degenerate rotator cuff disease
по: Cornell, HR
Опубликовано: (2011)

The role and regulation of Asterless in the centrosome cycle
по: Novak, ZA
Опубликовано: (2014)

Towards understanding the mechanism of cohesin loading
по: Dixon, SE
Опубликовано: (2013)

Functions of conserved centriole proteins in African trypanosomes
по: Scheumann, N
Опубликовано: (2012)

The role of protein arginine methylation in T-lymphocyte activation
по: Geoghegan, V, и др.
Опубликовано: (2012)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
по: Peterneva, K
Опубликовано: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
по: Halstead, J
Опубликовано: (2013)

The automated analysis and statistical characterisation of subcellular biological images
по: Li, S, и др.
Опубликовано: (2012)

Regulation and reproductive functions of membrane-bound vesicles secreted by the Drosophila male accessory gland
по: Corrigan, L
Опубликовано: (2014)

The role of ATF4 in hypoxia-induced cell death in cancer
по: Pike, L, и др.
Опубликовано: (2011)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
по: Duncan, T
Опубликовано: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
по: Khan, FF
Опубликовано: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
по: Portman, N
Опубликовано: (2011)

Structure-function studies of fibronectin domains in the human endometrium
по: Mok, M, и др.
Опубликовано: (2008)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
по: Zayer, A
Опубликовано: (2012)

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis
по: Meireles, A, и др.
Опубликовано: (2009)

The evolution of eukaryotic cilia
по: Hodges, M, и др.
Опубликовано: (2011)

The role of Topoisomerase II in replication in mammalian cells
по: Muftic, D
Опубликовано: (2011)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
по: Moss, J
Опубликовано: (2011)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
по: Fergusson, J, и др.
Опубликовано: (2015)

Segmentation of cell clumps for quantitative analysis
по: Li, S
Опубликовано: (2010)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
по: Gibson, K
Опубликовано: (2011)

The relation between multilocus population genetics and social evolution theory
по: Gardner, A, и др.
Опубликовано: (2007)

Synonymous codon usage influences the local protein structure observed
по: Saunders, R, и др.
Опубликовано: (2010)