Functional characterisation of synuclein-based novel genetic mouse models

Functional characterisation of synuclein-based novel genetic mouse models

<p>Synucleins are highly conserved presynaptic proteins with unknown function. α-synuclein plays a key role regulating dopamine homeostasis and is intimately involved in Parkinson’s disease (PD) pathogenesis. However, the normal/pathological role of α-synuclein remains unidentified. Studies ex...

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Bibliografiske detaljer
Hovedforfatter:	Anwar, S
Andre forfattere:	Wade-Martins, R
Format:	Thesis
Sprog:	English
Udgivet:	2011
Fag:	Neuroscience Medical Sciences Neurogenetics

Lignende værker

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Molecular Genetics of Language Impairment
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The role of polycomb repressive complex 2 in postnatal subventricular zone neural stem/progenitor cell self-renewal and multipotency
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Identification of the transneuronal homeostatic machinery at a central synapse
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GPER1 Signaling Initiates Migration of Female V-SVZ-Derived Cells
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Udgivet: (2020-05-01)

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Genetic architecture of declarative memory: implications for complex illnesses
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Udgivet: (2012)

Computational neurogenetic modeling /
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Udgivet: (2007)

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Characterisation of pitch: an early onset model of sensorineural deafness
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Udgivet: (2014)

Social Isolation and Enrichment Induce Unique miRNA Signatures in the Prefrontal Cortex and Behavioral Changes in Mice
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Udgivet: (2020-12-01)

Computational neuroscience : simulated demyelinating neuropathies and neuronopathies /
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Udgivet: (2013)

Hyperactive mTORC1 disrupts habenula function and light preference in zebrafish model of Tuberous sclerosis complex
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The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models
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Identification of epigenetic regulators of RNA editing mechanisms
af: Buss, G
Udgivet: (2023)

The genetics of handedness and dyslexia
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Udgivet: (2014)

Dissecting the functions of DISC1
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Udgivet: (2011)

The behavioural and molecular characterisation of a novel LRRK2 BAC transgenic rat model of Parkinson’s disease
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Functional investigation of microRNA pathways in human speech and language disorders
af: Ho, J
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Molecular and neural mechanisms of olfactory decision making in Drosophila melanogaster
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Udgivet: (2015)

Methods in genomic neuroscience /
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Udgivet: (2001)

Blood pressure and cerebral white matter share common genetic factors in Mexican Americans
af: Kochunov, P, et al.
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Reduced white matter integrity in sibling pairs discordant for bipolar disorder
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Investigating the roles of zinc finger homeobox 3 in circadian rhythms
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Model systems for exploring new therapeutic interventions and disease mechanisms in spinal muscular atrophies (SMAs)
af: Sleigh, JN
Udgivet: (2012)

Murine Cep290 phenotypes are modified by genetic backgrounds and provide an impetus for investigating disease modifier alleles [version 1; referees: 2 approved]
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Udgivet: (2015-08-01)

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes
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Fetal sex-specific epigenetic associations with prenatal maternal depressive symptoms
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Udgivet: (2022-09-01)

Using fast-scan cyclic voltammetry to investigate monoamine release in BAC transgenic rodent models of Parkinson's Disease
af: Potgieter, D
Udgivet: (2014)

Investigating rare genetic variants in common migraine
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Subplate populations in normal and pathological cortical development
af: Oeschger, F
Udgivet: (2011)

Molecular and behavioural characterisation of novel alpha-synuclein BAC transgenic mouse models of Parkinson's disease
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Udgivet: (2013)

Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain
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Udgivet: (2011)

Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies
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Udgivet: (2010)

Neuroanatomical screening and analysis of transgenic and ENU induced mutagenised mice
af: Edwards, A
Udgivet: (2011)