The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.

Hypoxia-inducible factor-1 (HIF) is regulated by oxygen-dependent prolyl hydroxylation. Of the three HIF prolyl hydroxylases (PHD1, 2 and 3) identified, PHD3 exhibits restricted substrate specificity in vitro and is induced in different cell types by diverse stimuli. PHD3 may therefore provide an in...

Полное описание

Библиографические подробности
Главные авторы:	Masson, N, Appelhoff, R, Tuckerman, JR, Tian, Y, Demol, H, Puype, M, Vandekerckhove, J, Ratcliffe, P, Pugh, C
Формат:	Journal article
Язык:	English
Опубликовано:	2004

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